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Methylation of glycosylated sphingolipid modulates membrane lipid topography and pathogenicity of Cryptococcus neoformans

In previous studies we showed that the replication of Cryptococcus neoformans in the lung environment is controlled by the glucosylceramide (GlcCer) synthase gene (GCS1), which synthesizes the membrane sphingolipid GlcCer from the C9-methyl ceramide. Here, we studied the effect of the mutation of th...

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Библиографические подробности
Главные авторы: Singh, Arpita, Wang, Haitao, Silva, Liana C., Na, Chongzheng, Prieto, Manuel, Futerman, Anthony H., Luberto, Chiara, Del Poeta, Maurizio
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302964/
https://ncbi.nlm.nih.gov/pubmed/22151739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2011.01735.x
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