Inhibition of mTOR activity in diabetes mellitus reduces proteinuria but not renal accumulation of hyaluronan

Objectives. Accumulation of extracellular matrix (ECM) components is an early sign of diabetic nephropathy. Also the glycosaminoglycan hyaluronan (HA) is elevated in the renal interstitium during experimental diabetes. The mammalian target of rapamycin (mTOR) pathway participates in the signaling of...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Ups J Med Sci
Main Authors: Stridh, Sara, Palm, Fredrik, Takahashi, Tomoko, Ikegami-Kawai, Mayumi, Hansell, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Informa Healthcare 2015
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816883/
https://ncbi.nlm.nih.gov/pubmed/26175092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03009734.2015.1062442
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker