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Inhibition of mTOR activity in diabetes mellitus reduces proteinuria but not renal accumulation of hyaluronan

Objectives. Accumulation of extracellular matrix (ECM) components is an early sign of diabetic nephropathy. Also the glycosaminoglycan hyaluronan (HA) is elevated in the renal interstitium during experimental diabetes. The mammalian target of rapamycin (mTOR) pathway participates in the signaling of...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Ups J Med Sci
मुख्य लेखकों: Stridh, Sara, Palm, Fredrik, Takahashi, Tomoko, Ikegami-Kawai, Mayumi, Hansell, Peter
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Informa Healthcare 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816883/
https://ncbi.nlm.nih.gov/pubmed/26175092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03009734.2015.1062442
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