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Robust Detection of DNA Hypermethylation of ZNF154 as a Pan-Cancer Locus with in Silico Modeling for Blood-Based Diagnostic Development

Sites that display recurrent, aberrant DNA methylation in cancer represent potential biomarkers for screening and diagnostics. Previously, we identified hypermethylation at the ZNF154 CpG island in 15 solid epithelial tumor types from 13 different organs. In this study, we measure the magnitude and...

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Bibliografiske detaljer
Udgivet i:J Mol Diagn
Main Authors: Margolin, Gennady, Petrykowska, Hanna M., Jameel, Nader, Bell, Daphne W., Young, Alice C., Elnitski, Laura
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816708/
https://ncbi.nlm.nih.gov/pubmed/26857064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2015.11.004
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