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Apolipoprotein E Receptor 2 mediates Activated Protein C-induced endothelial Akt activation and endothelial barrier stabilization
OBJECTIVE: Activated protein C (APC), a plasma serine protease, initiates cell signaling that protects endothelial cells from apoptosis and endothelial barrier disruption. Apolipoprotein E receptor 2 (ApoER2) (LRP8) is a receptor known for mediating signaling initiated by Reelin in neurons. ApoER2 c...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4816599/ https://ncbi.nlm.nih.gov/pubmed/26800564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306795 |
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