Chronic Heavy Alcohol Use is Associated with Upregulated Paneth Cell Antimicrobials in Gastric Mucosa

OBJECTIVES: How alcohol consumption affects the integrity and the defense mechanisms of the mucosa in the upper gastrointestinal tract is largely unknown. We examined the effect of heavy alcohol use on gastric and duodenal Paneth-cell-derived and epithelial antimicrobial peptides (AMPs), cytokines,...

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Bibliografiske detaljer
Udgivet i:Clin Transl Gastroenterol
Main Authors: Ostaff, M J, Schäfer, C, Courth, L, Stebe, S R D, Ott, G, Stange, E F, Wehkamp, J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Original Contributions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816256/
https://ncbi.nlm.nih.gov/pubmed/26181292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ctg.2015.26
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