Chronic Heavy Alcohol Use is Associated with Upregulated Paneth Cell Antimicrobials in Gastric Mucosa

OBJECTIVES: How alcohol consumption affects the integrity and the defense mechanisms of the mucosa in the upper gastrointestinal tract is largely unknown. We examined the effect of heavy alcohol use on gastric and duodenal Paneth-cell-derived and epithelial antimicrobial peptides (AMPs), cytokines,...

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Detalhes bibliográficos
Publicado no:Clin Transl Gastroenterol
Main Authors: Ostaff, M J, Schäfer, C, Courth, L, Stebe, S R D, Ott, G, Stange, E F, Wehkamp, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Contributions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816256/
https://ncbi.nlm.nih.gov/pubmed/26181292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ctg.2015.26
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