Paneth cell α-defensin 6 (HD-6) is an antimicrobial peptide

Defensins protect human barriers from commensal and pathogenic microorganisms. Human α-defensin 6 (HD-6) is produced exclusively by small intestinal Paneth cells but, in contrast to other antimicrobial peptides (AMPs) for HD-6, no direct antibacterial killing activity has been detected so far. Herei...

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Publicat a:Mucosal Immunol
Autors principals: Schroeder, B O, Ehmann, D, Precht, J C, Castillo, P A, Küchler, R, Berger, J, Schaller, M, Stange, E F, Wehkamp, J
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424388/
https://ncbi.nlm.nih.gov/pubmed/25354318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2014.100
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