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Acceleration of short and long DNA read mapping without loss of accuracy using suffix array

HPG Aligner applies suffix arrays for DNA read mapping. This implementation produces a highly sensitive and extremely fast mapping of DNA reads that scales up almost linearly with read length. The approach presented here is faster (over 20× for long reads) and more sensitive (over 98% in a wide rang...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Tárraga, Joaquín, Arnau, Vicente, Martínez, Héctor, Moreno, Raul, Cazorla, Diego, Salavert-Torres, José, Blanquer-Espert, Ignacio, Dopazo, Joaquín, Medina, Ignacio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816028/
https://ncbi.nlm.nih.gov/pubmed/25143289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu553
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