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Epigenetic regulators and their impact on therapy in acute myeloid leukemia

Genomic studies of hematologic malignancies have identified a spectrum of recurrent somatic alterations that contribute to acute myeloid leukemia initiation and maintenance, and which confer sensitivities to molecularly targeted therapies. The majority of these genetic events are small, site-specifi...

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Bibliographic Details
Published in:Haematologica
Main Authors: Pastore, Friederike, Levine, Ross L.
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815718/
https://ncbi.nlm.nih.gov/pubmed/26928248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.140822
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