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Epigenetic therapy combinations in acute myeloid leukemia: what are the options?
Epigenetics refers to the regulation of gene expression mainly by changes in DNA methylation and modifications of histone proteins without altering the actual DNA sequence. While epigenetic modifications are essential for normal cell differentiation, several driver mutations in leukemic pathogenesis...
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| Опубликовано в: : | Ther Adv Hematol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
SAGE Publications
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6348528/ https://ncbi.nlm.nih.gov/pubmed/30719265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620718816698 |
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