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Epigenetic therapy combinations in acute myeloid leukemia: what are the options?
Epigenetics refers to the regulation of gene expression mainly by changes in DNA methylation and modifications of histone proteins without altering the actual DNA sequence. While epigenetic modifications are essential for normal cell differentiation, several driver mutations in leukemic pathogenesis...
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| Publicado en: | Ther Adv Hematol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
SAGE Publications
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6348528/ https://ncbi.nlm.nih.gov/pubmed/30719265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620718816698 |
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