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Epigenetic therapy combinations in acute myeloid leukemia: what are the options?
Epigenetics refers to the regulation of gene expression mainly by changes in DNA methylation and modifications of histone proteins without altering the actual DNA sequence. While epigenetic modifications are essential for normal cell differentiation, several driver mutations in leukemic pathogenesis...
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| Udgivet i: | Ther Adv Hematol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
SAGE Publications
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6348528/ https://ncbi.nlm.nih.gov/pubmed/30719265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620718816698 |
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