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EPIGENETIC THERAPY IN ACUTE MYELOID LEUKEMIA: CURRENT AND FUTURE DIRECTIONS

Epigenetic modifications affect gene expression without changes in the actual DNA sequence. Two most important mechanisms include DNA methylation and histone tail modifications (especially acetylation and methylation). Epigenetic modulation is a part of normal physiologic development; its dysregulat...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Semin Hematol
Egile Nagusiak: Kim, Tae Kon, Gore, Steven D., Zeidan, Amer M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785931/
https://ncbi.nlm.nih.gov/pubmed/26111464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminhematol.2015.04.003
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