Plasmodium falciparum chloroquine resistance transporter (PfCRT) isoforms PH1 and PH2 perturb vacuolar physiology

BACKGROUND: Recent work has perfected yeast-based methods for measuring drug transport by the Plasmodium falciparum chloroquine (CQ) resistance transporter (PfCRT). METHODS: The approach relies on inducible heterologous expression of PfCRT in Saccharomyces cerevisiae yeast. In these experiments sele...

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Bibliografiske detaljer
Udgivet i:Malar J
Main Authors: Callaghan, Paul S., Siriwardana, Amila, Hassett, Matthew R., Roepe, Paul D.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815217/
https://ncbi.nlm.nih.gov/pubmed/27036417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1238-1
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