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β-TrCP-mediated ubiquitination and degradation of liver-enriched transcription factor CREB-H
CREB-H is an endoplasmic reticulum-resident bZIP transcription factor which critically regulates lipid homeostasis and gluconeogenesis in the liver. CREB-H is proteolytically activated by regulated intramembrane proteolysis to generate a C-terminally truncated form known as CREB-H-ΔTC, which translo...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4814919/ https://ncbi.nlm.nih.gov/pubmed/27029215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23938 |
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