Loading...

Impaired 17,20-Lyase Activity in Male Mice Lacking Cytochrome b(5) in Leydig Cells

Androgen and estrogen biosynthesis in mammals requires the 17,20-lyase activity of cytochrome P450 17A1 (steroid 17-hydroxylase/17,20-lyase). Maximal 17,20-lyase activity in vitro requires the presence of cytochrome b(5) (b5), and rare cases of b5 deficiency in human beings causes isolated 17,20-lya...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Endocrinol
Main Authors: Sondhi, Varun, Owen, Bryn M., Liu, Jiayan, Chomic, Robert, Kliewer, Steven A., Hughes, Beverly A., Arlt, Wiebke, Mangelsdorf, David J., Auchus, Richard J.
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814474/
https://ncbi.nlm.nih.gov/pubmed/26974035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1282
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!