Limited Expression of Cytochrome P450 17α-Hydroxylase/17,20-Lyase in Prostate Cancer Cell Lines

PURPOSE: Cytochrome P450 17α-hydroxylase/17,20-lyase (CYP17A1) is a key enzyme in the androgen biosynthesis pathway. CYP17A1 has been focused on because of the promising results of a potent CYP17A1 inhibitor in the treatment of castration-resistant prostate cancer (CRPC). A hypothesis that intratumo...

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Hlavní autoři: Jeong, Chang Wook, Yoon, Cheol Yong, Jeong, Seong Jin, Hong, Sung Kyu, Byun, Seok-Soo, Lee, Sang Eun
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Urological Association 2011
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151639/
https://ncbi.nlm.nih.gov/pubmed/21860772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4111/kju.2011.52.7.494
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