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How the kinetochore couples microtubule force and centromere stretch to move chromosomes

The Ndc80 complex (Ndc80, Nuf2, Spc24, Spc25) is a highly conserved kinetochore protein essential for end-on anchorage to spindle microtubule plus-ends and for force generation coupled to plus-end polymerization and depolymerization. Spc24/Spc25 at one end of the Ndc80 complex binds the kinetochore....

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Publicado en:Nat Cell Biol
Autores principales: Suzuki, Aussie, Badger, Benjamin L., Haase, Julian, Ohashi, Tomoo, Erickson, Harold P., Salmon, Edward D., Bloom, Kerry
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814359/
https://ncbi.nlm.nih.gov/pubmed/26974660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3323
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