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How the kinetochore couples microtubule force and centromere stretch to move chromosomes

The Ndc80 complex (Ndc80, Nuf2, Spc24, Spc25) is a highly conserved kinetochore protein essential for end-on anchorage to spindle microtubule plus-ends and for force generation coupled to plus-end polymerization and depolymerization. Spc24/Spc25 at one end of the Ndc80 complex binds the kinetochore....

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Bibliographic Details
Published in:Nat Cell Biol
Main Authors: Suzuki, Aussie, Badger, Benjamin L., Haase, Julian, Ohashi, Tomoo, Erickson, Harold P., Salmon, Edward D., Bloom, Kerry
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814359/
https://ncbi.nlm.nih.gov/pubmed/26974660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3323
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