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How the kinetochore couples microtubule force and centromere stretch to move chromosomes
The Ndc80 complex (Ndc80, Nuf2, Spc24, Spc25) is a highly conserved kinetochore protein essential for end-on anchorage to spindle microtubule plus-ends and for force generation coupled to plus-end polymerization and depolymerization. Spc24/Spc25 at one end of the Ndc80 complex binds the kinetochore....
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| Udgivet i: | Nat Cell Biol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4814359/ https://ncbi.nlm.nih.gov/pubmed/26974660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3323 |
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