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Cystatin C as a p53‐inducible apoptotic mediator that regulates cathepsin L activity

In response to various cellular stresses, p53 is activated and inhibits malignant transformation through the transcriptional regulation of its target genes. However, the full picture of the p53 downstream pathway still remains to be elucidated. Here we identified cystatin C, a major inhibitor of cat...

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Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Mori, Jinichi, Tanikawa, Chizu, Funauchi, Yuki, Lo, Paulisally Hau Yi, Nakamura, Yusuke, Matsuda, Koichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814261/
https://ncbi.nlm.nih.gov/pubmed/26757339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12881
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