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Regulation of iron homeostasis by the p53-ISCU pathway
Accumulation of iron in tissues increases the risk of cancer, but iron regulatory mechanisms in cancer tissues are largely unknown. Here, we report that p53 regulates iron metabolism through the transcriptional regulation of ISCU (iron-sulfur cluster assembly enzyme), which encodes a scaffold protei...
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| Yayımlandı: | Sci Rep |
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| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4642350/ https://ncbi.nlm.nih.gov/pubmed/26560363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16497 |
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