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Cystatin C as a p53‐inducible apoptotic mediator that regulates cathepsin L activity

In response to various cellular stresses, p53 is activated and inhibits malignant transformation through the transcriptional regulation of its target genes. However, the full picture of the p53 downstream pathway still remains to be elucidated. Here we identified cystatin C, a major inhibitor of cat...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Mori, Jinichi, Tanikawa, Chizu, Funauchi, Yuki, Lo, Paulisally Hau Yi, Nakamura, Yusuke, Matsuda, Koichi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814261/
https://ncbi.nlm.nih.gov/pubmed/26757339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12881
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