CLCA2 as a p53-Inducible Senescence Mediator

p53 is a tumor suppressor gene that is frequently mutated in multiple cancer tissues. Activated p53 protein regulates its downstream genes and subsequently inhibits malignant transformation by inducing cell cycle arrest, apoptosis, DNA repair, and senescence. However, genes involved in the p53-media...

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Main Authors: Tanikawa, Chizu, Nakagawa, Hidewaki, Furukawa, Yoichi, Nakamura, Yusuke, Matsuda, Koichi
Format: Artigo
Jezik:Inglês
Izdano: Neoplasia Press Inc. 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306259/
https://ncbi.nlm.nih.gov/pubmed/22431922
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