Hepatitis B virus X protein promotes human hepatoma cell growth via upregulation of transcription factor AP2α and sphingosine kinase 1

AIM: Sphingosine kinase 1 (SPHK1) is involved in various cellular functions, including cell growth, migration, apoptosis, cytoskeleton architecture and calcium homoeostasis, etc. As an oncogenic kinase, SPHK1 is associated with the development and progression of cancers. The aim of this study was to...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Lu, Zhan-ping, Xiao, Ze-lin, Yang, Zhe, Li, Jiong, Feng, Guo-xing, Chen, Fu-quan, Li, Ying-hui, Feng, Jin-yan, Gao, Yu-en, Ye, Li-hong, Zhang, Xiao-dong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814204/
https://ncbi.nlm.nih.gov/pubmed/26073327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.38
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