Long non-coding RNA HULC promotes tumor angiogenesis in liver cancer by up-regulating sphingosine kinase 1 (SPHK1)

Highly up-regulated in liver cancer (HULC) is a long non-coding RNA (lncRNA). We found that HULC up-regulated sphingosine kinase 1 (SPHK1), which is involved in tumor angiogenesis. Levels of HULC were positively correlated with levels of SPHK1 and its product, sphingosine-1-phosphate (S1P), in patie...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lu, Zhanping, Xiao, Zelin, Liu, Fabao, Cui, Ming, Li, Weiping, Yang, Zhe, Li, Jiong, Ye, Lihong, Zhang, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807995/
https://ncbi.nlm.nih.gov/pubmed/26540633
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