Hepatitis B virus X protein promotes hepatoma cell proliferation via upregulation of MEKK2

AIM: To investigate the mechanism underlying the increase of hepatoma cell proliferation by hepatitis B virus X protein (HBx). METHODS: HepG2, H7402 and HepG2.2.15 cells, which constitutively replicated hepatitis B virus were used. The effects of HBx on hepatoma cell proliferation were examined usin...

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Main Authors: Kong, Guang-yao, Zhang, Jun-ping, Zhang, Shuai, Shan, Chang-liang, Ye, Li-hong, Zhang, Xiao-dong
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003298/
https://ncbi.nlm.nih.gov/pubmed/21804577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.52
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