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Upregulation of sphingosine kinase 1 contributes to ventilator-associated lung injury in a two-hit model

Ventilator-associated lung injury (VALI) remains a significant medical problem in intensive care units. The present study aimed to investigate the role of sphingosine kinase 1 (SPHK1) in VALI using a two-hit model and explore the potential underlying molecular mechanism. Mice were divided into five...

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Detalhes bibliográficos
Publicado no:Int J Mol Med
Main Authors: Wang, Yan, Gao, Ting-Ting, Xu, Dun-Feng, Zhu, Xiao-Yan, Dong, Wen-Wen, Lv, Zhou, Liu, Yu-Jian, Jiang, Lai
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844625/
https://ncbi.nlm.nih.gov/pubmed/31638192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2019.4379
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