Reduced Expression of Galectin-9 Contributes to a Poor Outcome in Colon Cancer by Inhibiting NK Cell Chemotaxis Partially through the Rho/ROCK1 Signaling Pathway

Galectin-9 is a widely expressed protein that is involved in immune regulation and tumorpathogenesis and serves as a marker of a poor prognosis in various types of cancers. However, the clinical impact and the precise mechanism by which this protein contributes to colon tumor progression are unclear...

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Vydáno v:PLoS One
Hlavní autoři: Wang, Yang, Sun, Jintang, Ma, Chao, Gao, Wenjuan, Song, Bingfeng, Xue, Hao, Chen, Weiliang, Chen, Xi, Zhang, Yun, Shao, Qianqian, Wang, Qingjie, Zhao, Lei, Liu, Jia, Wang, Xiuwen, Wang, Huayang, Yang, Meixiang, Qu, Xun
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814049/
https://ncbi.nlm.nih.gov/pubmed/27028892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152599
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