Tim-3 Is Upregulated in NK Cells during Early Pregnancy and Inhibits NK Cytotoxicity toward Trophoblast in Galectin-9 Dependent Pathway

NK cells accumulate at the maternal-fetal interface (MFI) and play essential roles in maintaining immune tolerance during pregnancy. The mechanisms that facilitate NK cells tolerance to fetal tissue are largely unknown. T cell Ig and mucin domain-containing protein 3 (Tim-3) is a newly defined molec...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sun, Jintang, Yang, Meixiang, Ban, Yanli, Gao, Wenjuan, Song, Bingfeng, Wang, Yang, Zhang, Yun, Shao, Qianqian, Kong, Beihua, Qu, Xun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720443/
https://ncbi.nlm.nih.gov/pubmed/26789128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147186
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