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Rho GTPases orient directional sensing in chemotaxis

During chemotaxis, cells sense extracellular chemical gradients and position Ras GTPase activation and phosphatidylinositol (3,4,5)-triphosphate (PIP3) production toward chemoattractants. These two major signaling events are visualized by biosensors in a crescent-like zone at the plasma membrane. He...

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Hlavní autoři: Wang, Yu, Senoo, Hiroshi, Sesaki, Hiromi, Iijima, Miho
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856778/
https://ncbi.nlm.nih.gov/pubmed/24248334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312540110
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