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Rho GTPases orient directional sensing in chemotaxis
During chemotaxis, cells sense extracellular chemical gradients and position Ras GTPase activation and phosphatidylinositol (3,4,5)-triphosphate (PIP3) production toward chemoattractants. These two major signaling events are visualized by biosensors in a crescent-like zone at the plasma membrane. He...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3856778/ https://ncbi.nlm.nih.gov/pubmed/24248334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312540110 |
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