Increased expression of surface CD44 in hypoxia-DCs skews helper T cells toward a Th2 polarization

A low partial oxygen pressure (hypoxia) occurs in many pathological environments, such as solid tumors and inflammatory lesions. Understanding the cellular response to hypoxic stress has broad implications for human diseases. As we previously reported, hypoxia significantly altered dendritic cells (...

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Publicado no:Sci Rep
Main Authors: Yang, Meixiang, Liu, Yanguo, Ren, Guangwen, Shao, Qianqian, Gao, Wenjuan, Sun, Jintang, Wang, Huayang, Ji, Chunyan, Li, Xingang, Zhang, Yun, Qu, Xun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555176/
https://ncbi.nlm.nih.gov/pubmed/26323509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13674
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