Increased expression of surface CD44 in hypoxia-DCs skews helper T cells toward a Th2 polarization

A low partial oxygen pressure (hypoxia) occurs in many pathological environments, such as solid tumors and inflammatory lesions. Understanding the cellular response to hypoxic stress has broad implications for human diseases. As we previously reported, hypoxia significantly altered dendritic cells (...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Yang, Meixiang, Liu, Yanguo, Ren, Guangwen, Shao, Qianqian, Gao, Wenjuan, Sun, Jintang, Wang, Huayang, Ji, Chunyan, Li, Xingang, Zhang, Yun, Qu, Xun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555176/
https://ncbi.nlm.nih.gov/pubmed/26323509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13674
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