Leukemia-associated activating mutation of Flt3 expands dendritic cells and alters T cell responses

A common genetic alteration in acute myeloid leukemia is the internal tandem duplication (ITD) in FLT3, the receptor for cytokine FLT3 ligand (FLT3L). Constitutively active FLT3-ITD promotes the expansion of transformed progenitors, but also has pleiotropic effects on hematopoiesis. We analyzed the...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Exp Med
Main Authors: Lau, Colleen M., Nish, Simone A., Yogev, Nir, Waisman, Ari, Reiner, Steven L., Reizis, Boris
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2016
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813676/
https://ncbi.nlm.nih.gov/pubmed/26903243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150642
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker