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Insulin Receptor Substrate 1, the Hub Linking Follicle-stimulating Hormone to Phosphatidylinositol 3-Kinase Activation

The ubiquitous phosphatidylinositol 3-kinase (PI3K) signaling pathway regulates many cellular functions. However, the mechanism by which G protein-coupled receptors (GPCRs) signal to activate PI3K is poorly understood. We have used ovarian granulosa cells as a model to investigate this pathway, base...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Law, Nathan C., Hunzicker-Dunn, Mary E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813480/
https://ncbi.nlm.nih.gov/pubmed/26702053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.698761
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