Extracellular Signal-regulated Kinase (ERK)-dependent Phosphorylation of Y-Box-binding Protein 1 (YB-1) Enhances Gene Expression in Granulosa Cells in Response to Follicle-stimulating Hormone (FSH)

Within the ovarian follicle, immature oocytes are surrounded and supported by granulosa cells (GCs). Stimulation of GCs by FSH leads to their proliferation and differentiation, events that are necessary for fertility. FSH activates multiple signaling pathways to regulate genes necessary for follicul...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Donaubauer, Elyse M., Hunzicker-Dunn, Mary E.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933265/
https://ncbi.nlm.nih.gov/pubmed/27080258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.705368
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