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KIF17 regulates RhoA-dependent actin remodeling at epithelial cell–cell adhesions

The kinesin KIF17 localizes at microtubule plus-ends where it contributes to regulation of microtubule stabilization and epithelial polarization. We now show that KIF17 localizes at cell–cell adhesions and that KIF17 depletion inhibits accumulation of actin at the apical pole of cells grown in 3D or...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Sci
Prif Awduron: Acharya, Bipul R., Espenel, Cedric, Libanje, Fotine, Raingeaud, Joel, Morgan, Jessica, Jaulin, Fanny, Kreitzer, Geri
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Ltd 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813313/
https://ncbi.nlm.nih.gov/pubmed/26759174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.173674
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