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Direct Regulation of Microtubule Dynamics by KIF17 Motor and Tail Domains

KIF17 is a kinesin-2 family motor that interacts with EB1 at microtubule (MT) plus-ends and contributes to MT stabilization in epithelial cells. The mechanism by which KIF17 affects MTs and how its activity is regulated are not yet known. Here, we show that EB1 and the KIF17 autoinhibitory tail doma...

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Autori principali: Acharya, Bipul R., Espenel, Cedric, Kreitzer, Geri
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820867/
https://ncbi.nlm.nih.gov/pubmed/24072717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.494989
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