KIF17 regulates RhoA-dependent actin remodeling at epithelial cell–cell adhesions

The kinesin KIF17 localizes at microtubule plus-ends where it contributes to regulation of microtubule stabilization and epithelial polarization. We now show that KIF17 localizes at cell–cell adhesions and that KIF17 depletion inhibits accumulation of actin at the apical pole of cells grown in 3D or...

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Vydáno v:J Cell Sci
Hlavní autoři: Acharya, Bipul R., Espenel, Cedric, Libanje, Fotine, Raingeaud, Joel, Morgan, Jessica, Jaulin, Fanny, Kreitzer, Geri
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813313/
https://ncbi.nlm.nih.gov/pubmed/26759174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.173674
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