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KIF17 regulates RhoA-dependent actin remodeling at epithelial cell–cell adhesions

The kinesin KIF17 localizes at microtubule plus-ends where it contributes to regulation of microtubule stabilization and epithelial polarization. We now show that KIF17 localizes at cell–cell adhesions and that KIF17 depletion inhibits accumulation of actin at the apical pole of cells grown in 3D or...

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Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Acharya, Bipul R., Espenel, Cedric, Libanje, Fotine, Raingeaud, Joel, Morgan, Jessica, Jaulin, Fanny, Kreitzer, Geri
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813313/
https://ncbi.nlm.nih.gov/pubmed/26759174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.173674
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