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Polarization-Dependent Selective Transport to the Apical Membrane by KIF5B in MDCK Cells

Microtubule-based vesicular transport is well documented in epithelial cells, but the specific motors involved and their regulation during polarization are largely unknown. We demonstrate that KIF5B mediates post-Golgi transport of an apical protein in epithelial cells, but only after polarity has d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jaulin, Fanny, Xue, Xiaoxiao, Rodriguez-Boulan, Enrique, Kreitzer, Geri
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712496/
https://ncbi.nlm.nih.gov/pubmed/17925227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.08.001
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