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Discovery of Small Molecule Inhibitors to Krüppel-Like Factor 10 (KLF10): Implications for Modulation of T Regulatory Cell Differentiation

The Krüppel-like family of transcription factors (KLFs) constitute a subfamily of C(2)H(2)-type zinc finger proteins with distinct cell-type expression patterns and regulate functional aspects of cell growth and differentiation, activation, or development. KLF10 has been previously shown to critical...

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Detalles Bibliográficos
Publicado en:J Med Chem
Autores principales: Khedkar, Santosh A., Sun, Xinghui, Rigby, Alan C., Feinberg, Mark W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811605/
https://ncbi.nlm.nih.gov/pubmed/25581017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm5018187
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