Structural basis for the recruitment of the human CCR4–NOT deadenylase complex by Tristetraprolin

Tristetraprolin (TTP) is an RNA binding protein that controls the inflammatory response by limiting the expression of several proinflammatory cytokines. TTP post-transcriptionally represses gene expression by interacting with AU-rich elements (AREs) in 3′UTRs of target mRNAs and subsequently engende...

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Publicat a:Nat Struct Mol Biol
Autors principals: Fabian, Marc R., Frank, Filipp, Rouya, Christopher, Siddiqui, Nadeem, Lai, Wi S., Karetnikov, Alexey, Blackshear, Perry J., Nagar, Bhushan, Sonenberg, Nahum
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811204/
https://ncbi.nlm.nih.gov/pubmed/23644599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2572
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