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Structural basis for the recruitment of the human CCR4–NOT deadenylase complex by Tristetraprolin

Tristetraprolin (TTP) is an RNA binding protein that controls the inflammatory response by limiting the expression of several proinflammatory cytokines. TTP post-transcriptionally represses gene expression by interacting with AU-rich elements (AREs) in 3′UTRs of target mRNAs and subsequently engende...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Fabian, Marc R., Frank, Filipp, Rouya, Christopher, Siddiqui, Nadeem, Lai, Wi S., Karetnikov, Alexey, Blackshear, Perry J., Nagar, Bhushan, Sonenberg, Nahum
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811204/
https://ncbi.nlm.nih.gov/pubmed/23644599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2572
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