Structural basis for the recruitment of the human CCR4–NOT deadenylase complex by Tristetraprolin

Tristetraprolin (TTP) is an RNA binding protein that controls the inflammatory response by limiting the expression of several proinflammatory cytokines. TTP post-transcriptionally represses gene expression by interacting with AU-rich elements (AREs) in 3′UTRs of target mRNAs and subsequently engende...

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Bibliografische gegevens
Gepubliceerd in:Nat Struct Mol Biol
Hoofdauteurs: Fabian, Marc R., Frank, Filipp, Rouya, Christopher, Siddiqui, Nadeem, Lai, Wi S., Karetnikov, Alexey, Blackshear, Perry J., Nagar, Bhushan, Sonenberg, Nahum
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811204/
https://ncbi.nlm.nih.gov/pubmed/23644599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2572
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