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Structural basis for the recruitment of the human CCR4–NOT deadenylase complex by Tristetraprolin
Tristetraprolin (TTP) is an RNA binding protein that controls the inflammatory response by limiting the expression of several proinflammatory cytokines. TTP post-transcriptionally represses gene expression by interacting with AU-rich elements (AREs) in 3′UTRs of target mRNAs and subsequently engende...
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Publicado no: | Nat Struct Mol Biol |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4811204/ https://ncbi.nlm.nih.gov/pubmed/23644599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2572 |
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