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HIV-1 Antibody Neutralization Breadth Is Associated with Enhanced HIV-Specific CD4(+) T Cell Responses

Antigen-specific CD4(+) T helper cell responses have long been recognized to be a critical component of effective vaccine immunity. CD4(+) T cells are necessary to generate and maintain humoral immune responses by providing help to antigen-specific B cells for the production of antibodies. In HIV in...

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Bibliographic Details
Published in:J Virol
Main Authors: Ranasinghe, Srinika, Soghoian, Damien Z., Lindqvist, Madelene, Ghebremichael, Musie, Donaghey, Faith, Carrington, Mary, Seaman, Michael S., Kaufmann, Daniel E., Walker, Bruce D., Porichis, Filippos
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Cellular Response to Infection
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810720/
https://ncbi.nlm.nih.gov/pubmed/26656715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02278-15
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