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Early Preservation of CXCR5(+) PD-1(+) Helper T Cells and B Cell Activation Predict the Breadth of Neutralizing Antibody Responses in Chronic HIV-1 Infection

Much is known about the characteristics of broadly neutralizing antibodies (bNAbs) generated during HIV-1 infection, but little is known about immunological mechanisms responsible for their development in only a minority of those infected by HIV-1. By monitoring longitudinally a cohort of HIV-1-infe...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Cohen, Kristen, Altfeld, Marcus, Alter, Galit, Stamatatos, Leonidas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249103/
https://ncbi.nlm.nih.gov/pubmed/25210168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02186-14
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