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Infection by Herpes Simplex Virus 1 Causes Near-Complete Loss of RNA Polymerase II Occupancy on the Host Cell Genome

Lytic infection by herpes simplex virus 1 (HSV-1) triggers a change in many host cell programs as the virus strives to express its own genes and replicate. Part of this process is repression of host cell transcription by RNA polymerase II (Pol II), which also transcribes the viral genome. Here, we d...

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Publicado en:J Virol
Main Authors: Abrisch, Robert G., Eidem, Tess M., Yakovchuk, Petro, Kugel, Jennifer F., Goodrich, James A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810688/
https://ncbi.nlm.nih.gov/pubmed/26676778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02665-15
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