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B2 RNA represses TFIIH phosphorylation of RNA polymerase II

Mouse B2 RNA represses RNA polymerase II (Pol II) transcription during the cellular heat shock response. B2 RNA binds Pol II, enters complexes at promoters, and keeps the polymerase from engaging the DNA. Here we show that phosphorylation of Ser5 residues in the Pol II carboxy terminal domain (CTD)...

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Bibliographic Details
Main Authors: Yakovchuk, Petro, Goodrich, James A, Kugel, Jennifer F
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023648/
https://ncbi.nlm.nih.gov/pubmed/21326911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.2.1.14306
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