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Dissecting Herpes Simplex Virus 1-Induced Host Shutoff at the RNA Level
Herpes simplex virus 1 (HSV-1) induces a profound host shutoff during lytic infection. The virion host shutoff (vhs) protein plays a key role in this process by efficiently cleaving host and viral mRNAs. Furthermore, the onset of viral DNA replication is accompanied by a rapid decline in host transc...
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| Publicado no: | J Virol |
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| Main Authors: | , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7925104/ https://ncbi.nlm.nih.gov/pubmed/33148793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01399-20 |
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