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Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation

Eukaryotic gene expression is extensively regulated by cellular stress and pathogen infections. We have previously shown that herpes simplex virus 1 (HSV-1) and several cellular stresses cause widespread disruption of transcription termination (DoTT) of RNA polymerase II (RNAPII) in host genes and t...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Wang, Xiuye, Liu, Liang, Whisnant, Adam W., Hennig, Thomas, Djakovic, Lara, Haque, Nabila, Bach, Cindy, Sandri-Goldin, Rozanne M., Erhard, Florian, Friedel, Caroline C., Dölken, Lars, Shi, Yongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7971895/
https://ncbi.nlm.nih.gov/pubmed/33684133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009263
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