Peripheral T Follicular Helper Cells Are the Major HIV Reservoir within Central Memory CD4 T Cells in Peripheral Blood from Chronically HIV-Infected Individuals on Combination Antiretroviral Therapy

In this study, we examined the peripheral blood (PB) central memory (T(CM)) CD4(+) T cell subsets designated peripheral T follicular helper cells (pTfh cells) and non-pTfh cells to assess HIV permissiveness and persistence. Purified pTfh and non-pTfh cells from healthy HIV-negative donors were teste...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Pallikkuth, Suresh, Sharkey, Mark, Babic, Dunja Z., Gupta, Sachin, Stone, Geoffrey W., Fischl, Margaret A., Stevenson, Mario, Pahwa, Savita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810658/
https://ncbi.nlm.nih.gov/pubmed/26676775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02883-15
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