Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein

The von Hippel-Lindau tumor suppressor protein (pVHL) negatively regulates hypoxia-inducible mRNAs such as the mRNA encoding vascular endothelial growth factor (VEGF). This activity has been linked to its ability to form multimeric complexes that contain elongin C, elongin B, and Cul2. To understand...

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Bibliografische gegevens

Gepubliceerd in:	J Clin Invest
Hoofdauteurs:	Ohh, Michael, Takagi, Yuichiro, Aso, Teijiro, Stebbins, Charles E., Pavletich, Nikola P., Zbar, Bert, Conaway, Ronald C., Conaway, Joan Weliky, Kaelin, William G.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Clinical Investigation 1999
Onderwerpen:	Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC481054/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10587522/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8161
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